Azathioprine induced pancreatitis, polyarthritis and panniculitis (PPP) syndrome in a patient with Crohn’s disease
| Journal | Volume 83 - 2020 |
| Issue | Fasc.1 - Case reports |
| Author(s) | S. Mishra 1, S. Garg 1, R. Mahajan 1, A. Patil 1, P. Bhatia 1, V. Sharma 1 |
| Full article |
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Affiliations: (1) Department of Gastroenterology, Internal Medicine, Dermatology, Clinical Pharmacology and Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India
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Azathioprine and 6-mercaptopurine have been widely used for maintenance of remission in patients with inflammatory bowel disease. The use of thiopurines is associated with multiple adverse effects including dose dependent cytopenias or idiosyncratic reaction. We report about a case of azathioprine related pancreatitis associated with polyarthralgia and panniculitis. Pancreatitis, polyarthritis and panniculitis (PPP) syndrome is an uncommon phenomenon which may accompany a number of pancreatic diseases including acute or chronic pancreatitis or pancreatic malignancy. To the best of our knowledge, this is the first report of Azathioprine related PPP syndrome. Keywords: panniculitis, pancreatitis, thiopurine, Crohn’s disease, inflammatory bowel disease, azathioprine. |
| The authors declare that they have no conflict of interest. |
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© Acta Gastro-Enterologica Belgica. PMID 32233278 |
